Borussia Dortmund will make the trip to Czech Republic having got their Champions League campaign underway with a goalless draw against Barcelona.
They face a team in Slavia Prague who shared points with Inter Milan.
Dortmund have recorded back-to-back 2-2 draws in the Bundesliga, leaving the club down in eighth position in the standings.
Slavia Prague form: WWDWWW
Borussia Dortmund form: WLWDDD
Slavia Prague possible starting lineup: Kolar; Coufal, Kudela, Hovorka, Boril; Traore, Husbauer, Soucek; Stanciu; Masopust, Olayinka
Borussia Dortmund possible starting lineup: Burki; Piszczek, Akanji, Hummels, Hakimi; Delaney, Witsel; Sancho, Reus, Brandt; Alcacer
Genk vs. Napoli – prediction
Genk host Napoli in the Champions League on Wednesday evening looking to bounce back from their 6-2 drubbing at the hands of Red Bull Salzburg on Matchday One.
Carlo Ancelotti‘s men will be looking for another three points against their Belgian opponents will put them a step closer to securing a top-two spot in Group E come December 10.
Genk form: WDLLWW
Napoli form: LWWWLW
Genk possible starting lineup: Coucke; Maehle, Dewaest, Lucumi, Uronen; Ito, Berge, Hrosovsky, Ndongala; Heynen; Samatta
Napoli possible starting lineup: Ospina; Lorenzo, Koulibaly, Rui, Ghoulam; Callejon, Allan, Ruiz, Zielinski; Mertens, Insigne
Liverpool vs. Red Bull Salzburg -prediction
Liverpool welcome Red Bull Salzburg to Anfield on Wednesday night looking to kick start their Champions League defense after losing their opener in Naples.
A 2-0 defeat to Napoli has left the holders fighting for top spot in Group E, and this game promises to be another difficult test against a Salzburg side that hit six goals past Genk on matchday one.
Salzburg thrashed Genk 6-2 on matchday one, the team’s tally of 55 goals in just 12 games across all competitions would worry any defense in football, with Salzburg scoring five or more goals in seven of those outings, four or more in nine and at least twice in every game.
Liverpool form: WWLWWW
Red Bull Salzburg form: WWWDWW
Liverpool possible starting lineup:
Adrian; Alexander-Arnold, Matip, Van Dijk, Robertson; Oxlade-Chamberlain, Fabinho, Milner; Salah, Firmino, Mane
Salzburg possible starting lineup:
Stankovic; Kristensen, Ramalho, Wober, Ulmer; Szoboszlai, Junuzovic, Mwepu, Minamino; Hwang, Koita