Manchester United who finished sixth last season travel to face the team who ended up with nine points place lower Wolves.
Wolves faced Manchester United three times in last season with the Midlands club winning twice and drawing the other.
Will it be another loss trip to Molineux for Ole Gunnar Solskjær’s team?
Wolves finished seventh place last year which means they have been partaking in the UEFA Europa League qualifiers.
Wolves first competitive game of this season was way back on July 25 against Crusaders of Northern Ireland, A 2-0 home win followed by a 4-1 victory in Belfast saw them ease through.
In the third qualifying round, Wolves met FC Pyunik from Armenia and eased to a 4-0 win in Yerevan in the first leg.
Last Thursday, Wolves then won the second leg at home by the same 4-0 scoreline to secure their biggest ever European aggregate win.
Coming up this Thursday, Wolves be in Turin to face Serie A side Torino.
But first, Nuno Espírito Santo and his team will be have to focus on their first Premier League home game of the season.
All of this European involvement means that, last weekend, means Wolves kicked off a top-flight campaign on a Sunday for the very first time.
They made a short 59 mile trip across the Midlands to face Leicester City.
and on the hour, Leander Dendoncker thought he’d scored the winning goal, but after video review, it was adjudged that Willy Boly had handled the ball in the build-up.
No goal and 0-0 it finished at the King Power Stadium.
As for the visitors, Ole Gunnar Solskjær side hosted Chelsea last Sunday in a at Old Trafford.
After just 18 minutes, the Manchester United took the lead when they were awarded a penalty which Marcus Rashford smashed in the opening goal.
Chelsea on the other hand hit the woodwork on two separate occasions so Man United were certainly living dangerously.
20 minutes into the second period, Jesse Lingard’s cross was bundled in by Anthony Martial who made it 2-0 for Manchester United.
A matter of seconds later, 95 to be exact, Paul Pogba played in Rashford who made it 3-0.
Before the end, debutant Daniel James scored his first goal for the club to seal an emphatic home win for the red devils.
That was their biggest victory over Chelsea in a top-flight match since a 4-0 win back in March 1965.
Raúl Jiménez will lead the line for Wolves. He is 5/1 to score first and 11/5 to get the ball at the back of the net anytime.
He’ll be alongside Diogo Jota who has a 11/2 to score first and 5/2 to score in 90 minutes.
Anthony Martial is Manchester United number nine once more with a 5/1 to break the deadlock and 9/4 to make it two this season.
Marcus Rashford also scored last weekend and has a 5/1 to score first and 9/4 to score anytime.
Both Jota and Raúl Jiménez to score.
Both Rashford and Martial to score.
Both Scott McTominay and Jesse Lingard to score.